- Precise Systems, Inc. (Edgewood, MD)
- …cell lines + Perform screening of compounds of interest and their effect on ion channel activity, whether that be in cell lines, induced pluripotent stem ... the patch clamp technique (automated, manual or both) + Understanding of ion channel physiology, cell signaling associated with channel function and… more
- New York University (New York, NY)
- …novel protein regulators of ion channels; approaches to targeting the ion channel complexes in neuropathic pain and neurodegenerative diseases; discovery of ... We seek a highly motivated and creative individual interested in how ion channels, specifically, voltage-gated calcium and sodium channels, are regulated by novel… more
- New York University (New York, NY)
- …novel protein regulators of ion channels; approaches to targeting the ion channel complexes in neuropathic pain and neurodegenerative diseases; discovery of ... We seek a highly motivated and creative individual interested in how ion channels, specifically, voltage-gated calcium and sodium channels, are regulated by novel… more
- New York University (New York, NY)
- …novel protein regulators of ion channels; approaches to targeting the ion channel complexes in neuropathic pain and neurodegenerative diseases; discovery of ... We seek a highly motivated and creative individual interested in how ion channels, specifically, voltage-gated calcium and sodium channels, are regulated by novel… more
- University of Colorado (Aurora, CO)
- …interests in the Department currently include cardiac and skeletal muscle physiology, ion channel biophysics, molecular physiology, cell signaling, sensory and ... complement and/or extend the Department's existing research strengths in ion channels, molecular biophysics, membrane protein physiology, neuroscience, sensory… more
- Bristol Myers Squibb (Princeton, NJ)
- …scientific leadership for cell-based assays + Expertise in the application of GPCR, ion channel , and transporter technologies and methodologies and ability to ... knowledge of complex cell surface receptor pharmacology including GPCR, ion channels and transporters is required. + Extensive experience...for a range of drug modalities + Knowledge of ion flux technologies such as FLIPR and/or FDSS and… more
- dsm-firmenich (San Diego, CA)
- …computational programming skills a plus. + Hands-on experience designing and performing ion - channel and receptor-based assays a plus. + Excellent team spirit, ... will possess a deep understanding of the neural pathways, receptors and ion channels which drive insect behaviour. Broad hands-on experience with cellular and… more
- University of Southern California (Los Angeles, CA)
- …studies aimed at understanding cellular and molecular mechanisms of taste sensation and ion channel biophysics. The laboratory recently discovered a new family ... of ion channels (Tu et al , Science, 2018; http://science.sciencemag.org/content/359/6379/1047 ). One of the members of this family, OTOP1, functions in taste cells… more
- Pennsylvania State University (Hershey, PA)
- …cultures from animals. The candidate will also be involved in mitochondrial ion channel studies using electrophysiology and microscopy techniques. Other ... responsibilities include ordering lab supplies and routine maintenance of laboratory equipment. Qualified candidates should have a bachelor's or master's degree in chemistry, biology, physics, or related areas. The preference will be given to applicants with… more
- University Of Vermont (Burlington, VT)
- …research project designed to understand the control of brain blood flow and vascular ion channel contribution to blood flow regulation. Assist in development and ... implementation of experiments relating to mouse brain microcirculation (eg electrophysiology, imaging, and behavioral studies). Prepare solutions, biochemical and molecular assays; maintain transgenic and conventional animal colonies; perform small animal… more
- Houston Methodist (Houston, TX)
- …models, in vitro and in vivo optogenetic manipulation of GSCs, and high throughput ion channel drug screening. Positions are open for both projects immediately. ... The positions are supported from the following grants: "Patterned optogenetic neuromodulation to reprogram glioma stem cells". 1R21NS127229 "A multiplexed high-throughput platform to report pharmacologic alteration of cancer stem cell membrane potential and… more
- UCLA Health (Los Angeles, CA)
- …on elucidating the mechanism of disease for periodic paralysis and myotonia, resulting from ion channel mutations, and then to leverage this knowledge for the ... design and preclinical testing of disease modifying agents in our knock-in mutant mouse models. The Lab Assistant will be the primary operator to perform muscle dissection and contraction studies on samples harvested from our mouse models. Qualifications… more
- University of Colorado (Aurora, CO)
- …and folding mechanisms of transmembrane proteins on the endoplasmic reticulum, such as ion channel proteins and cell receptors. We apply diverse approaches in ... the study, including state-of-art single-molecule tracking as well as traditional biochemistry and biophysics approaches, such as ELISA, western blots, immunofluorescence, immunoprecipitation, circular dichroism, ITC, and DSC. The lab is successful in… more
- University of Colorado (Aurora, CO)
- …and folding mechanisms of transmembrane proteins on the endoplasmic reticulum, such as ion channel proteins and cell receptors. We apply diverse approaches in ... the study, including state-of-art single-molecule tracking as well as traditional biochemistry and biophysics approaches, such as ELISA, western blots, immunofluorescence, immunoprecipitation, circular dichroism, ITC, and DSC. The lab is successful in… more
- University of Rochester (Rochester, NY)
- …and cell adhesion signaling, G protein-coupled receptor pharmacology and signaling, and ion channel structure and function. + Department faculty research ... programs use pharmacological and physiological approaches/analyses to address significant unresolved problems in health and disease. + Applicants with research interests in all areas in pharmacology and physiology are encouraged to apply. **Job Highlights** +… more
- OmniAb (Emeryville, CA)
- …OmniAb are also core capabilities for the discovery and screening of high-value ion channel and transporter targets. OmniAb consists of dynamic, collaborative ... and innovative team members that are passionate about contributing to the technological frontier of drug discovery and to the advancement of global human health. Together, with our partners, we are enabling the discovery of next-generation therapeutics. About… more
- University of Maryland, Baltimore (Baltimore, MD)
- …recording and/or Ca2imaging techniques, experience with zebrafish models, knowledge of ion channel biophysics and/or muscle physiology, etc.). The University ... of Maryland, Baltimore is an Equal Opportunity/Affirmative Action Employer. Minorities, women, protected veterans and individuals with disabilities are encouraged to apply. **Job:** **Postdoctoral Fellows* **Organization:** **School of Medicine - Clinical… more
- University of Maryland, Baltimore (Baltimore, MD)
- …be involved in a project investigating the role of polycystins complex as a distinct ion channel and in primary cilia in kidney physiology and disease. The ... project will also involve the functional regulation of polycystin-1 by the cleavage at the G-protein coupled receptor proteolysis site (GPS) motif, a key posttranslational modification of the protein, in cell signaling. The laboratory is highly collaborative… more
- University of Maryland, Baltimore (Baltimore, MD)
- …technical expertise (ie,experience with patch-clamp recording techniques and knowledge of ion channel biophysics and/or muscle physiology). The University of ... Maryland, Baltimore is an Equal Opportunity/Affirmative Action Employer. Minorities, women, protected veterans and individuals with disabilities are encouraged to apply. **Job:** **Postdoctoral Fellows* **Organization:** **School of Medicine - Clinical… more
- GE HealthCare (Arlington Heights, IL)
- …manometers) + Equipment used for the quantification of radioactive isotopes (ie, ion chambers, multi- channel analyzers, scintillation detectors) + Maintain all ... calibration history files for manufacturing equipment. + Perform periodic reviews and updates of calibration SOPs and department records. + Perform Preventative Maintenance on equipment and instrumentation as required / assigned. + Troubleshoot equipment with… more