- Cedars-Sinai (Los Angeles, CA)
- …Cancer Center. Our research group has an established track record in the study of metabolic pathways using in vivo and ex vivo multi-omics approaches, ... unique opportunity within the research group is to establish in vivo mouse models to study metabolic changes in the heart during cancer. Currently, a particular… more
- Merck (South San Francisco, CA)
- …of In vivo Pharmacology with strong experience in cardiovascular and metabolic diseases to join our Quantitative Biosciences (Pharmacology) department as an in ... and passionate team. **Key responsibilities:** + Develop and support in vivo pharmacology strategies for obesity, immuno- metabolic , and cardiovascular diseases… more
- WuXi AppTec (San Diego, CA)
- …HD Biosciences, a WuXi AppTec company is searching for a Director- In Vivo Pharmacology to manage team and project operations. The candidate must provide leadership, ... objectives. This key position will report directly to the head of In Vivo Pharmacology Department. **Responsibilities** * Leads multifunctional teams in the In … more
- MD Anderson Cancer Center (Houston, TX)
- …assays (such as drug screening, flow cytometry, development of resistant cell lines, metabolic profiling) and in vivo experiments using xenograft, syngeneic and ... focus on overcoming resistance to targeted therapies, identifying targetable metabolic adaptations, and enhancing response to immunotherapy. Applicants with… more
- Merck (South San Francisco, CA)
- …for FIH + Independently design, plan, and conduct in vitro or in vivo experiments using effective techniques to produce high-quality data that supports decision ... and energy expenditure, hypothalamic inflammation in the context of metabolic disease, metabolism and with a track record of...neurobiology + Proficiency in both in vitro and in vivo techniques, with extensive bench experience + Ability to… more
- Merck (South San Francisco, CA)
- …will be responsible for overseeing and facilitating the research in metabolic disorders & inflammation, in the Cardiometabolic Disease (CMD) Discovery Biology ... across the globe. **Responsibilities include:** + Develop therapeutic strategies for immuno- metabolic diseases and build a robust pipeline of drug discovery… more
- Boehringer Ingelheim (Athens, GA)
- …enzyme/protein, bioanalytical, pharmacologic screening, cell- or tissue-based methods and/or in vivo disease models. + Working knowledge of assays and methods used ... + Experience preparing and executing in vitro and in vivo assays SOPs and protocols, and in data collection...+ Experience preparing and executing in vitro and in vivo assays SOPs and protocols, and in data collection… more
- Pennsylvania State University (University Park, PA)
- …neuroanatomy, microdissection for genetic analyses, confocal microscopy, stereotaxic surgery, in vivo optogenetics, and metabolic characterization. It will also ... require competence in using a wide range of molecular and in vivo experimental techniques. Work will include rodent behavioral testing (feeding, motivation,… more
- Rockefeller University (New York, NY)
- …and genes to identify effector functions, 2) mouse models of inflammatory and metabolic diseases, and 3) in vivo validation of bacterial metabolites and ... genes in human cohorts. Overview The Laboratory of Genetically Encoded Small Molecules at The Rockefeller University has an immediate opening for a synthetic/peptide chemist. The focus of the research will be on the chemical synthesis of natural product like… more
- UCLA Fielding School of Public Health (Los Angeles, CA)
- …such spectral flow cytometry, proteomic assays, confocal microscopy, and in vivo imaging in conditional knockout mouse models; 2) performing unbiased screens ... and how these affect cellular responses to stress; and, 4) developing new ex vivo models from human lung specimens for investigating the pathogenesis of lung injury… more
- University of Colorado (Aurora, CO)
- …executing and analyzing data from research projects aimed at understanding metabolic dependencies impacting the biology and function of B-ALL resistance to ... executing and analyzing data from research projects aimed at understanding metabolic dependencies impacting the biology and function of B-ALL resistance to… more
- UCLA Fielding School of Public Health (Los Angeles, CA)
- …to apply. The postdoctoral associate will lead the molecular imaging and in vivo model development of this exciting collaborative research initiative and will be ... responsible for: * Establishing in vivo models of immune-mediated islet graft rejection * Development...diabetes research * Experience with mouse models of diabetes, metabolic disorders, or immunology * Experience with quantitative analyses… more
- Florida Atlantic University (Jupiter, FL)
- …and tissue imaging techniques to study mechanisms of neuronal dysfunction. In Vivo Studies: Conducting research using mouse models to explore mechanisms of disease ... progression. Experimental Procedures: Cell culture and analysis of metabolic and functional state; cell imaging; iPSC-derived brain cells; western blots;… more
- Stanford University (Stanford, CA)
- …ChEM-H) the overarching goal is to understand the molecular pathways of metabolic homeostasis. We use metabolomics and proteomics technologies as discovery tools. We ... novel biological mechanisms and potential therapeutic targets to treat metabolic disease. The successful candidate will lead projects that...have the capacity to develop in vitro and in vivo skills to test the involvement of novel pathways… more
- University of Southern California (Los Angeles, CA)
- …researcher who is interested in the field of liver disease (eg metabolic liver disease, viral hepatitis, liver inflammation, and hepatic immunity). The candidate ... is expected to have significant experience with in vitro and vivo experiments, including but not limited to primary cell isolation/culture, general molecular… more
- Merck (South San Francisco, CA)
- …responsible for the design, execution, and interpretation of complex in vitro/ex vivo assays and mechanistic experimentation to advance early drug discovery projects ... studies to advance a diverse drug discovery pipeline targeting obesity, immune- metabolic , and cardiovascular disorders. In addition, this role will participate in… more
- University of Utah (Salt Lake City, UT)
- …We are interested in candidates who are passionate about inherited metabolic disorders, specifically those involving congenital disorders of glycosylation ( CDG ... candidates with documented research skills and experience combining innovative in vivo and in vitro approaches for investigating pathophysiology and developing… more
- University of Colorado (Aurora, CO)
- …manner using advanced biomedical research techniques (in vitro and in vivo experimentation as independent and team-oriented work), project planning, data ... journals (as first author or co-author) is preferred. + Experience with in vivo tumor and cachexia modeling, animal handling and tissue dissection is preferred. +… more
- Mount Sinai Health System (New York, NY)
- …to develop efficient and safe interventions for preventing and treating metabolic diseases. Her recent publications include Cell Metabolism, Journal of Hepatology, ... technologies used in the lab include transgenic mouse models, human genetics, metabolic studies, stem cell biology, next generation sequencing, and a variety of… more
- Merck (South San Francisco, CA)
- …pharmacologist with extensive drug discovery expertise in cardiovascular and metabolic diseases to join our Quantitative Biosciences (Pharmacology) department. The ... responsible for the design, execution, and interpretation of complex in vitro/ex vivo assays as well as mechanistic experimentation to advance drug discovery from… more