• Principal Scientist , Preclinical…

    Merck (South San Francisco, CA)
    …(DPS) group based in South San Francisco, CA is seeking an Principal Scientist with small molecule and peptide experience. DPS is a multi-disciplinary ... solid state crystal form characterization, pre-formulation and formulation support and small molecule and biologics developability assessments at the development… more
    Merck (12/03/25)
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  • Principal Scientist - TS/MS API…

    Lilly (Indianapolis, IN)
    …essential to our patients around the world. The API EM Senior or Principal Scientist will join the Technical Services/Manufacturing Sciences (TS/MS) team who ... technical support and scientific expertise across Peptides and Oligonucleotides (TIDES). The Senior/ Principal Scientist acts as an SME responsible for providing… more
    Lilly (10/07/25)
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  • Senior Principal Scientist , Pre

    Pfizer (San Diego County, CA)
    **ROLE SUMMARY** This Senior Principal Scientist position will be a strong scientific and leadership role within the Early Formulation Science and Drug Delivery ... forms, and impacts of solid form on stability, manufacturability, and bio-performance of small molecule drug candidates and drug products + Efficient application… more
    Pfizer (11/19/25)
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  • Senior / Principal Scientist

    Boehringer Ingelheim (Ridgefield, CT)
    …Drug Substance-Drug Product Interface organization, driving innovation in small molecule development. The Principal Scientist /Sr. Scientist ... **Description** Boehringer Ingelheim is currently seeking a Senior or Principal Scientist to support our Material and Analytical Sciences team to join our… more
    Boehringer Ingelheim (11/20/25)
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  • Senior Principal Scientist , Peptide…

    Genentech (South San Francisco, CA)
    …We are seeking a highly motivated and experienced Medicinal Chemist (Senior Principal Scientist ) to join our innovative research and development team. ... proficiency in both automated solid-phase peptide synthesis, and solution-phase small molecule synthesis, utilizing state-of-the-art protecting group and… more
    Genentech (11/06/25)
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  • Principal Scientist , Drug…

    Merck (West Point, PA)
    scientist for the Drug Metabolism and Pharmacokinetics (DMPK) group. The Principal Scientist will be a key contributor to multi-disciplinary drug development ... to the discovery and clinical development of therapeutics across various modalities. The Principal Scientist will guide the design and interpretation of in… more
    Merck (12/12/25)
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  • Principal Scientist , Computational…

    Frontier Medicines (Boston, MA)
    …Medicines is seeking a highly motivated individual to fill the position of Principal Scientist , Computational Chemistry. The successful candidate will play a ... and properties, and make design suggestions to improve the profiles of small molecule drug candidates. As a covalent drug discovery-focused company, there is the… more
    Frontier Medicines (11/04/25)
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  • Principal Scientist /Sr.…

    Lilly (Indianapolis, IN)
    …make our group better. + Demonstrate learning agility across modalities (eg small molecule , peptide and oligonucleotide). + Help formulate commercial ... chemical engineering or related field. **Additional Skills/Preferences:** + Experience with small molecule organic synthesis, knowledge of reaction mechanisms,… more
    Lilly (11/17/25)
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  • Principal Scientist - Data Foundry…

    Lilly (Indianapolis, IN)
    …who are determined to make life better for people around the world. **Lilly Small Molecule Discovery** is an organization purpose-built to create molecules that ... established function within this organization. Its mission is to accelerate molecule discovery by building highly optimized foundational platforms, streamlining lab… more
    Lilly (11/11/25)
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  • Associate Principal Scientist

    Merck (South San Francisco, CA)
    …Pharmacokinetics, Dynamics, Metabolism and Bioanalytics (PDMB) group is seeking an Associate Principal Scientist to contribute to our Company's biologics, drug ... conjugates, and novel modality discovery and development pipeline. The Associate Principal Scientist will be primarily discovery team-facing and is expected to… more
    Merck (12/04/25)
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  • Principal Research Scientist

    AbbVie (North Chicago, IL)
    …experience with technical report writing.Technical understanding and experience with small molecule products manufacturing, development, quality and analytics ... Job Description Purpose: The PDS&T Parenterals/Eye Care group is seeking a motivated Scientist as a CMC drug product project lead, specifically for parenteral drug… more
    AbbVie (12/04/25)
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  • Postdoctoral Scientist , Turkson Lab

    Cedars-Sinai (Los Angeles, CA)
    Principal Investigator and other Research Scientists, the Postdoctoral Scientist will perform routine and complex laboratory procedures throughout training ... grant funds. **Key Responsibilities** + Design, synthesize, purify, and characterize small - molecule compounds. + Perform structure elucidation using 1H/13C/1⁹F… more
    Cedars-Sinai (10/01/25)
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  • Director, Head of Biochemical Lead Profiling

    Takeda Pharmaceuticals (Boston, MA)
    …experience, including managing and developing scientific teams at the senior scientist / principal scientist level. + Excellent cross-functional collaboration ... driving implementation of highly efficient, AI-integrated DMTA (Design-Make-Test-Analyze) cycles for small and large- molecule discovery. In this leadership role,… more
    Takeda Pharmaceuticals (12/10/25)
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