• Senior Principal Scientist

    Merck (San Francisco, CA)
    …to ensure timely and equitable access to our medicines. The Senior Principal Scientist has primary responsibility for protocol development and medical/scientific ... leadership through interaction with key scientific leaders. **Specifically, the Senior Principal Scientist is responsible for:** + Planning clinical trials… more
    Merck (12/02/25)
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  • Principal Scientist I

    Genentech (Pleasanton, CA)
    …better tomorrow. **The Opportunity** We are seeking a highly motivated and innovative Principal Scientist to join our Molecular Diagnostics R&D team in ... future of molecular diagnostics at Roche. **Your Role and Responsibilities** As a Principal Scientist , you will lead from the bench and be a key technical leader… more
    Genentech (12/11/25)
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  • Principal Scientist , Nasal Sprays

    Kelly Services (South San Francisco, CA)
    Kelly(R) Science & Clinical is seeking a Principal Scientist for a **remote** direct hire opportunity with one of our clients, a neuroscience-focused ... at Hiring Experts. **Workplace: Remote (US)** **Pay:** 160,000-190,000/year **Position title:** Principal Scientist , Nasal Sprays **Position type:** Direct hire… more
    Kelly Services (11/21/25)
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  • Principal Scientist - Clinical…

    Amgen (South San Francisco, CA)
    …Join us and transform the lives of patients while transforming your career. ** Principal Scientist - Clinical Pharmacology, Modeling & Simulation** **What you ... Clinical Pharmacology, Modeling & Simulation Department at Amgen is seeking a Principal Scientist . In this vital role, you will drive innovative modeling and… more
    Amgen (09/22/25)
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  • Senior Principal Scientist

    Merck (South San Francisco, CA)
    **Job Description** **Senior Principal Scientist Translational Medicine, Immunology** Translational Medicine in our Research & Development Division is ... Therapeutic Area Lead in Translational Medicine. **Primary responsibilities for the Senior Principal Scientist include the following:** + Key member of an… more
    Merck (12/03/25)
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  • Associate Principal Scientist

    Merck (South San Francisco, CA)
    …seeking an exceptional and experienced scientist in the role of Associate Principal Scientist in the South San Francisco Discovery Biologics group. The ... qualified candidate will be a scientist with a breadth and depth of expertise in immunization-based antibody discovery, including but not limited to expertise in… more
    Merck (12/12/25)
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  • Associate Principal Scientist

    Merck (South San Francisco, CA)
    …Pharmacokinetics, Dynamics, Metabolism and Bioanalytics (PDMB) group is seeking an Associate Principal Scientist to contribute to our Company's biologics, drug ... conjugates, and novel modality discovery and development pipeline. The Associate Principal Scientist will be primarily discovery team-facing and is expected to… more
    Merck (12/04/25)
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  • Principal Scientist , Group Leader,…

    Genentech (South San Francisco, CA)
    **The Position** **The Opportunity** We are seeking an exceptional Principal Scientist (Group Leader) to join our world-class Antibody Engineering Department, ... areas + Drive innovation to solve them through antibody engineering Our new Scientist /Group Lead will help shape the future of our antibody drug capabilities and… more
    Genentech (12/06/25)
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  • Principal Scientist , Preclinical…

    Merck (South San Francisco, CA)
    …Pharmaceutical Sciences (DPS) group based in South San Francisco, CA is seeking an Principal Scientist with small molecule and peptide experience. DPS is a ... multi-disciplinary research group that provides drug delivery, solid state crystal form characterization, pre-formulation and formulation support and small molecule and biologics developability assessments at the development and drug discovery interface. Our… more
    Merck (12/03/25)
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  • Associate Principal Scientist

    Merck (South San Francisco, CA)
    …Enabling Capabilities (Analytical R&D) is seeking applicants for an Associate Principal Scientist position available at our research laboratories located ... in South San Francisco, California. The successful candidate must be able to collaborate in a dynamic, integrated, and multidisciplinary team environment. A broad range of tools (eg high-resolution mass spectrometry, chromatography, spectroscopy) are… more
    Merck (12/02/25)
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  • Senior Principal Scientist

    Merck (South San Francisco, CA)
    **Job Description** The Senior Director (Sr. Principal Scientist ) has primary responsibility for the strategic planning and directing clinical research ... activities involving investigational compounds in Immunology. With a focus on late-stage development, the Senior Clinical Director will manage the entire cycle of clinical development, including determination of appropriate disease indications to pursue and… more
    Merck (12/02/25)
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  • Senior Principal Scientist , Peptide…

    Genentech (South San Francisco, CA)
    …We are seeking a highly motivated and experienced Medicinal Chemist (Senior Principal Scientist ) to join our innovative research and development team. ... This is a technical leadership position within our Peptide Therapeutics department, focused on advancing Peptide Therapeutics. The ideal candidate will be a significant contributor and a proven leader, responsible for optimizing and advancing novel peptide… more
    Genentech (11/06/25)
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  • Principal Scientist , Computational…

    Frontier Medicines (South San Francisco, CA)
    …Medicines is seeking a highly motivated individual to fill the position of Principal Scientist , Computational Chemistry. The successful candidate will play a ... leading role in developing medicinal chemistry optimization strategies for key drug discovery programs. This individual will review experimental results, develop SAR hypotheses for activity, selectivity, and properties, and make design suggestions to improve… more
    Frontier Medicines (11/04/25)
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  • Lab Head, Principal Scientist

    Genentech (South San Francisco, CA)
    …is thrilled to announce a unique opportunity for a highly skilled, highly motivated Principal Scientist to lead a lab-based research group. We seek an ... exceptional candidate with expertise in the biology of hormone-dependent cancers, specifically of the breast and prostate, who will be dedicated to discovering and developing new therapies. The successful candidate will work closely with our Drug Development,… more
    Genentech (10/29/25)
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  • Principal Applied Scientist

    Amazon (San Francisco, CA)
    …the development of industry-leading technology with multimodal systems. As a Principal Scientist within the Artificial General Intelligence (AGI) organization, ... General Intelligence (AGI) team is looking for a passionate, talented, and inventive Principal Applied Scientist with a strong deep learning background, to lead… more
    Amazon (11/19/25)
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  • Principal Applied Scientist

    Unity Technologies (San Francisco, CA)
    **San Francisco, CA, USA** ** Principal Applied Scientist ** Location San Francisco, CA, USA Department Engineering Requisition ID JOBREQ-2515113 **Role ... how large models perceive and understand 3D worlds. We're looking for a Principal Applied Scientist to lead this work. In this role, you'll focus on advancing… more
    Unity Technologies (12/05/25)
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  • Principal Applied Scientist , Amazon…

    Amazon (San Francisco, CA)
    …General Intelligence (AGI) team is looking for a passionate, talented, and inventive Principal Applied Scientist with a strong deep learning and generative AI ... development of software development skills of Nova foundational models. As a Principal Applied Scientist , you are a trusted part of the technical leadership. You… more
    Amazon (11/20/25)
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  • Principal Data Scientist

    Abbott (Alameda, CA)
    …114,000 colleagues serve people in more than 160 countries. **The Opportunity:** Our Principal Data Scientist will work out of our Alameda, California location. ... This individual works as an integral part of a collaborative data and analytics team and responsible for analyzing real-world data to generate insights and develop machine learning models that drive the development and optimization of devices in Abbott… more
    Abbott (11/04/25)
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  • Principal Data Scientist

    Intuit (San Francisco, CA)
    …cross-functional collaboration, all aimed at uncovering and scaling growth opportunities. As a Principal Data Scientist , you will operate at a senior technical ... level as an individual contributor, partnering closely with peers and leaders alike to identify, execute, and iterate on high-impact growth initiatives. Your role is pivotal in leveraging advanced data science techniques, including causal inference-to unlock… more
    Intuit (10/30/25)
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  • Principal Applied Scientist , FAR…

    Amazon (San Francisco, CA)
    …AI pioneers to lead key initiatives in robotic intelligence. As a Principal Applied Scientist , you'll spearhead the development of breakthrough foundation ... models that enable robots to perceive, understand, and interact with the world in unprecedented ways. You'll drive technical excellence in areas such as perception, manipulation, science understanding, sim2real transfer, multi-modal foundation models, and… more
    Amazon (09/24/25)
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